Diet. Give no milk or milk products. All foods must be cooked.
Adrenocorticosteroids. Give prednisone, 20 to 60mg orally daily, and reduce by 5mg per week when there is clinical and sigmoidoscopic evidence of improvement. Hydrocortisone enemas, 100mg each night, may provide additional anti-inflammatory effect.

Antimicrobial therapy. Sulfasalazine, 2 to 4g daily in divided doses, has been shown to be beneficial in reducing inflammation and in decreasing the frequency of recurrent attack in this form of the disease. It has been suggested that
5-aminosalicylic acid is the active moiety of sulfasalazine. Sulfasalazine has been shown to decrease the number and motility of sperms and increase the frequency of abnormal sperms. Infertility may occur during the treatment period.

Mild disease
These patients have minimal evidence of inflammatory bowel disease,asymptomatic rectal bleeding, minimal involvement by sigmoidoscopic examination, and on systemic signs of the disease.

Diet. Give no milk products.
Antimicrobial therapy. Sulfasalazine, 2 to 4g daily in divided doses as prolonged maintenance therapy.
Adrenocorticosteroids. Hydrocortisone enemas or suppositories, 100mg each night until lesion heals or disease has been stable for several months.

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